NovaDBMX
For Reliable Bone Regeneration
CompositionNovaDBMX is an innovative bone graft substitute designed to promote bone regeneration. It consists of demineralzied bone matrix bound to bone morphogenetic protein (BMP) complex at three times physiological levels, integrated into a biocompatible gel putty. This formulation is delivered in a convenient prefilled syringe, ensuring ease of application and precise delivery to the surgical site. The BMP complex, a member of the transforming growth factor-beta (TGF-β) superfamily, is a potent osteoinductive agent that stimulates mesenchymal stem cells to differentiate into osteoblasts, facilitating new bone formation. The gel putty serves as a scaffold, providing temporary structural support and enabling controlled release of the BMP complex to optimize bone regeneration.UsesNovaDBMX is indicated for use in orthopedic, maxillofacial, and periodontal surgeries to repair bone defects where the body’s natural healing capacity is insufficient.
PRIMARY APPLICATIONS
o Orthopedic Surgery: NovaDBMX supports spinal fusions (e.g., anterior lumbar interbody fusion), treatment of long bone nonunions, and repair of traumatic bone defects, reducing the need for autogenous bone grafts.
o Maxillofacial Surgery: It is used for alveolar ridge augmentation, sinus floor augmentation, and reconstruction of mandibular defects, particularly in cases associated with tooth extraction or trauma.
o Periodontal Surgery: NovaDBMX aids in regenerating periodontal tissues, including alveolar bone, periodontal ligament, and cementum, for conditions such as intra-bony defects and grade II molar furcation defects.The prefilled syringe allows for precise application, making it suitable for both open surgical procedures and minimally invasive techniques.Benefits
NovaDBMX ADVANTAGES
Enhanced Bone Regeneration: The high-potency BMP complex at three times physiological levels accelerates osteogenesis, promoting faster and more robust bone formation compared to standard grafts.
Elimination of Donor Site Morbidity: By serving as an alternative to autogenous bone grafts, NovaDBMX eliminates the need for bone harvesting, reducing patient pain, complications, and recovery time.
Ease of Use: The prefilled syringe and gel putty formulation simplify surgical application, ensuring consistent delivery and adaptability to various defect sizes and shapes.
Versatility: NovaDBMX is effective across multiple specialties, addressing a wide range of bone defects in orthopedic, maxillofacial, and periodontal contexts
Reduced Risk of Graft Failure: The controlled release of BMP minimizes complications such as ectopic bone formation and enhances integration with host tissue.
NovaDBMX represents a cutting-edge solution for bone regeneration, offering clinicians a reliable and efficient tool to improve patient outcomes
While we do not endorse any off-label use of our products, it has been used in the following cases;
M84.3-: Stress fractureM84.4-: Pathological fractureM84.5-: Pathological fracture in neoplastic diseaseM84.6-: Pathological fracture in other diseasesMosteomyelitisM86.6-: Other chronic osteomyelitisM96.0: Pseudarthrosis after fusion or arthrodesisM96.1e, not elsewhere classified: Fracture of nasal bonesS02.3-: Fracture of orbital floorS02.4-: Fracture of malar, maxillary, and zygoma bonesS02.5-: Fracture of tooth (traumatic)S02.6-le: Dislocation of jawK02.3: Arrested dental cariesK04.5: Chronic apical periodontitisK05.2-: Aggressive periodontitisK05.3-: Chronic periodontitisK08.2-: Atrophy of edentulous alveolar ridgeM27.2: Inflammatory conditions of jawsM27.3: Alveolitis of jawsS32.0-: Fracture of lumbar vertebraS32.1-: Fracture of coccyxS72.0-: Fracture of head and neck of femurS82.0-: Fracture of patellaS82.1-: Fracture of upper end of tibiaS82.2-: Fracture of shaft of tibiaS82.3-: Fracture of lower end of tibia.
